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Nelle ultime 24 ore si sono registrati 34764 nuovi casi positivi al #coronavirus e 692 decessi per #Covid-19. Il rapporto tra i nuovi casi e i 237 mila tamponi effettuati è sceso al 14,6%. Significa che risulta positivo circa un test su sette. I numeri del giorno segnalano un contagio sostanzialmente stabile.

Il #manifesto
#italia

Purtroppo senza link....
 

Tocilizumab: Arthritis drug may treat severe Covid | BBC News

The rheumatoid arthritis drugs tocilizumab appears to treat people who are critically ill with Covid-19, early trial data shows.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 

Tocilizumab: Arthritis drug may treat severe Covid | BBC News

The rheumatoid arthritis drugs tocilizumab appears to treat people who are critically ill with Covid-19, early trial data shows.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 
So klar beschrieb die Deutsche Botschaft in China die Anfänge von Covid-19:

->Januar 2020: Coronavirus-Berichte aus BRD-Botschaft in Peking ,,,

Buzzfeed veröffentlicht 180 Seiten Lageberichte des Auswärtigen Amtes und kommentiert:
BuzzFeed News Deutschland veröffentlicht nun die Coronavirus-Lageberichte der deutschen Botschaft in China aus den ersten Wochen diesen Jahres im Original. Die Berichte zeigen ein klares Bild der sich täglich verschärfenden Lage im chinesischen Wuhan. Quasi gleichzeitig sprach Gesundheitsminister Jens Spahn damals davon, dass es für übertriebene Sorge keinen Grund gebe.
#covid-19 #corona #brd #deutschland
 

T-cell Covid immunity 'present in adults six months after first infection' | World news | The Guardian

Cellular (T-cell) immunity against the virus that causes Covid-19 is likely to be present within most adults six months after primary infection, with levels considerably higher in patients with symptoms, a study suggests.
The data offers another piece of the puzzle that could be key to understanding whether previous Sars-CoV-2 infections – the virus behind Covid-19 – can prevent reinfection, and if so, for how long.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 

T-cell Covid immunity 'present in adults six months after first infection' | World news | The Guardian

Cellular (T-cell) immunity against the virus that causes Covid-19 is likely to be present within most adults six months after primary infection, with levels considerably higher in patients with symptoms, a study suggests.
The data offers another piece of the puzzle that could be key to understanding whether previous Sars-CoV-2 infections – the virus behind Covid-19 – can prevent reinfection, and if so, for how long.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 
Click thru to read the whole thread.

There is one place in the world where a map of #COVID19 cases & deaths reveals a straight line, with a huge amount of disease on one side, very little on the other | Laurie Garrett on Twitter

The 3000+ mile border US/#Canada It's stark. MORE https://t.co/GB87cNcSXD" / Twitter
https://twitter.com/Laurie_Garrett/status/1321627987847139329

#CoronaVirus #covid-19 #pandemic #US #Canada #politics #USPolitics #health #medicine
 
Click thru to read the whole thread.

There is one place in the world where a map of #COVID19 cases & deaths reveals a straight line, with a huge amount of disease on one side, very little on the other | Laurie Garrett on Twitter

The 3000+ mile border US/#Canada It's stark. MORE https://t.co/GB87cNcSXD" / Twitter
https://twitter.com/Laurie_Garrett/status/1321627987847139329

#CoronaVirus #covid-19 #pandemic #US #Canada #politics #USPolitics #health #medicine
 

The airborne lifetime of small speech droplets and their potential importance to SARS-CoV-2 transmission | Zenodo

Movies that show the experimental setup and the full 85-minute observation of speech droplet nuclei.

The full movie recording of highly sensitive laser light scattering observations that indicate loud-speaking generates, in addition to hundreds of regular droplets, also many thousands of micro-droplets per second. This movie clip shows the decay of airborne particles.
https://zenodo.org/record/3770559#.X5szhtT7SCP

#covid-19 #CoronaVirus #pandemic #SARS-CoV-2 #speech #health #aerosol #aerosols #particles #physics #science
 

The airborne lifetime of small speech droplets and their potential importance to SARS-CoV-2 transmission | Zenodo

Movies that show the experimental setup and the full 85-minute observation of speech droplet nuclei.

The full movie recording of highly sensitive laser light scattering observations that indicate loud-speaking generates, in addition to hundreds of regular droplets, also many thousands of micro-droplets per second. This movie clip shows the decay of airborne particles.
https://zenodo.org/record/3770559#.X5szhtT7SCP

#covid-19 #CoronaVirus #pandemic #SARS-CoV-2 #speech #health #aerosol #aerosols #particles #physics #science
 

The FDA just approved the first coronavirus drug – but this new medicine might be even better | BGR


Very interesting.
Researchers tested a cancer drug called plitidepsin as a coronavirus therapy and discovered it can block the virus’s ability to replicate.

The use of plitidepsin reduced viral loads after just seven days and improved blood test markers for inflammation.

Nearly 40% of a limited group of patients who received various doses of plitidepsin were discharged after just eight days in the hospital.
https://bgr.com/2020/10/25/coronavirus-treatment-plitidepsin-cancer-drug-spain-trial/

#covid-19 #CoronaVirus #health #medicine #virus
The FDA just approved the first coronavirus drug – but this new medicine might be even better
 

The FDA just approved the first coronavirus drug – but this new medicine might be even better | BGR


Very interesting.
Researchers tested a cancer drug called plitidepsin as a coronavirus therapy and discovered it can block the virus’s ability to replicate.

The use of plitidepsin reduced viral loads after just seven days and improved blood test markers for inflammation.

Nearly 40% of a limited group of patients who received various doses of plitidepsin were discharged after just eight days in the hospital.
https://bgr.com/2020/10/25/coronavirus-treatment-plitidepsin-cancer-drug-spain-trial/

#covid-19 #CoronaVirus #health #medicine #virus
The FDA just approved the first coronavirus drug – but this new medicine might be even better
 
#covid-19
 
#covid-19
 
Merkblatt zur aktuellen #COVID-19 Testung in der Schweiz

PCR/NAT
Die PCR (Polymerase-Kettenreaktion) ist eine NAT (Nucleic Acid Amplification Technology)-
Methode, der modernen Molekularbiologie um in einer Probe vorhandene Nukleinsäure (RNA oder
DNA) in vitro zu vervielfältigen und danach mit geeigneten Detektionssystemen nachzuweisen. Der
Nachweis der Nukleinsäure gibt jedoch #keinen #Rückschluss auf das Vorhandensein eines
#infektiösen #Erregers. Dies kann nur mittels eines #Virusnachweises und einer #Vermehrung in der
#Zellkultur erfolgen.

(Stand: 20.05.2020)
https://www.bag.admin.ch/dam/bag/de/dokumente/mt/k-und-i/aktuelle-ausbrueche-pandemien/2019-nCoV/merkblatt-swissmedic-covid-19-testung.pdf.download.pdf/Merkblatt_zur_aktuellen_COVID-19_Testung_in_der_Schweiz_Swissmedic_BAG.pdf
 
Merkblatt zur aktuellen #COVID-19 Testung in der Schweiz

PCR/NAT
Die PCR (Polymerase-Kettenreaktion) ist eine NAT (Nucleic Acid Amplification Technology)-
Methode, der modernen Molekularbiologie um in einer Probe vorhandene Nukleinsäure (RNA oder
DNA) in vitro zu vervielfältigen und danach mit geeigneten Detektionssystemen nachzuweisen. Der
Nachweis der Nukleinsäure gibt jedoch #keinen #Rückschluss auf das Vorhandensein eines
#infektiösen #Erregers. Dies kann nur mittels eines #Virusnachweises und einer #Vermehrung in der
#Zellkultur erfolgen.

(Stand: 20.05.2020)
https://www.bag.admin.ch/dam/bag/de/dokumente/mt/k-und-i/aktuelle-ausbrueche-pandemien/2019-nCoV/merkblatt-swissmedic-covid-19-testung.pdf.download.pdf/Merkblatt_zur_aktuellen_COVID-19_Testung_in_der_Schweiz_Swissmedic_BAG.pdf
 

Masks can protect you from more severe COVID-19, experts say - Los Angeles Times

Cloth face masks still provide a major protective benefit: They filter out a majority of viral particles.

As it turns out, that’s pretty important. Breathing in a small amount of virus may lead to no disease or a more mild infection. But inhaling a huge volume of virus particles can result in serious disease or death.
So wear the fcking mask!
#masks #corona #covid-19
 

Can You Become Reinfected With Covid-19? It's Very Unlikely, Experts Say - The New York Times

Reports of reinfection instead may be cases of drawn-out illness. A decline in antibodies is normal after a few weeks, and people are protected from the coronavirus in other ways.
#corona #covid-19

The New York Times: Can You Get Covid-19 Again? It’s Very Unlikely, Experts Say (By Apoorva Mandavilli)

 

Masks offer much more protection against coronavirus than many think | Los Angeles Times

There’s a common refrain that masks don’t protect you; they protect other people from your own germs, which is especially important to keep unknowingly infected people from spreading the coronavirus.
But now, there’s mounting evidence that masks also protect you.
If you’re unlucky enough to encounter an infectious person, wearing any kind of face covering will reduce the amount of virus that your body will take in.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 

Masks offer much more protection against coronavirus than many think | Los Angeles Times

There’s a common refrain that masks don’t protect you; they protect other people from your own germs, which is especially important to keep unknowingly infected people from spreading the coronavirus.
But now, there’s mounting evidence that masks also protect you.
If you’re unlucky enough to encounter an infectious person, wearing any kind of face covering will reduce the amount of virus that your body will take in.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 
15.06.2020 Ärzteblatt: Studie: Mund-Nasen-Schutz wichtiger als Social Distancing #Coronavirus #TeamMaskeAuf
 

Coronavirus came to UK 'on at least 1,300 separate occasions' | BBC News

Coronavirus was brought into the UK on at least 1,300 separate occasions, a major analysis of the genetics of the virus shows.
The study, by the Covid-19 Genomics UK consortium (Cog-UK), completely quashes the idea that a single "patient zero" started the whole UK outbreak.
The analysis also finds China, where the pandemic started, had a negligible impact on cases in the UK.
Instead those initial cases came mostly from European countries.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 

Coronavirus came to UK 'on at least 1,300 separate occasions' | BBC News

Coronavirus was brought into the UK on at least 1,300 separate occasions, a major analysis of the genetics of the virus shows.
The study, by the Covid-19 Genomics UK consortium (Cog-UK), completely quashes the idea that a single "patient zero" started the whole UK outbreak.
The analysis also finds China, where the pandemic started, had a negligible impact on cases in the UK.
Instead those initial cases came mostly from European countries.
#science #medicine #health #Covid-19 #CoronaVirus #pandemic
 
Bypassing clinical trials of COVID-19 vaccine 'catastrophic,' says editorial

http://global.chinadaily.com.cn/a/202005/23/WS5ec88c5ca310a8b241157ca4.html

Bypassing clinical trials of a potential vaccine for #SARS-CoV-2, the virus causing #COVID-19, would be "catastrophic," said an editorial published on #Science Advances on Friday.

It is "vital to take time" to ensure any vaccine candidate's safety and investigate potential adverse effects, said the editorial by Douglas Green, deputy editor of the multidisciplinary scientific journal.

A vaccine able to trigger strong neutralizing antibody responses in #clinical tests will still not be ready for widespread implementation without comprehensive safety tests, wrote Green, who is also an expert on #immunology.

Vaccines must be examined for causing an effect known as antibody-dependent enhancement, whereby #vaccine-induced #antibodies that bind to the #virus also attach to the body's #cells, facilitating #infection of these cells -- a concerning phenomenon that has been observed in vaccines against #dengue, #Ebola, #HIV, and #feline #coronavirus, said the editorial.

Ethical accelerated testing on humans "should not be ruled out completely," but extreme risks must be weighed against potential benefits, it said.

There are currently 95 vaccines under development against SARS-CoV-2, with most expected to clear phase one, and two already moving into phase two trials, it added.
 
Bypassing clinical trials of COVID-19 vaccine 'catastrophic,' says editorial

http://global.chinadaily.com.cn/a/202005/23/WS5ec88c5ca310a8b241157ca4.html

Bypassing clinical trials of a potential vaccine for #SARS-CoV-2, the virus causing #COVID-19, would be "catastrophic," said an editorial published on #Science Advances on Friday.

It is "vital to take time" to ensure any vaccine candidate's safety and investigate potential adverse effects, said the editorial by Douglas Green, deputy editor of the multidisciplinary scientific journal.

A vaccine able to trigger strong neutralizing antibody responses in #clinical tests will still not be ready for widespread implementation without comprehensive safety tests, wrote Green, who is also an expert on #immunology.

Vaccines must be examined for causing an effect known as antibody-dependent enhancement, whereby #vaccine-induced #antibodies that bind to the #virus also attach to the body's #cells, facilitating #infection of these cells -- a concerning phenomenon that has been observed in vaccines against #dengue, #Ebola, #HIV, and #feline #coronavirus, said the editorial.

Ethical accelerated testing on humans "should not be ruled out completely," but extreme risks must be weighed against potential benefits, it said.

There are currently 95 vaccines under development against SARS-CoV-2, with most expected to clear phase one, and two already moving into phase two trials, it added.
 

Recovered COVID-19 patients test positive but not infectious, data finds | Ars Technica

People who recover from COVID-19 but test positive for the virus again days or weeks later are not shedding viral particles and are not infectious, according to data released Tuesday by the Korea Centers for Disease Control and Prevention.
#science #medicine #health #Covid-19 #CoronaVirus
 

Recovered COVID-19 patients test positive but not infectious, data finds | Ars Technica

People who recover from COVID-19 but test positive for the virus again days or weeks later are not shedding viral particles and are not infectious, according to data released Tuesday by the Korea Centers for Disease Control and Prevention.
#science #medicine #health #Covid-19 #CoronaVirus
 
18.05.2020 Telepolis: WHO warnt vor zweiter tödlicher Covid-19-Welle #Coronavirus #Covid-19 #Coronakrise
 
In case you missed this:中共军校数据 :中国至少64万确诊
Leaked #Chinese #Virus Database Covers 230 Cities, 640,000 Updates #covid19 #covid-19 #coronavirus
Leaked Chinese Virus Database Covers 230 Cities, 640,000 Updates
 
In case you missed this:中共军校数据 :中国至少64万确诊
Leaked #Chinese #Virus Database Covers 230 Cities, 640,000 Updates #covid19 #covid-19 #coronavirus
Leaked Chinese Virus Database Covers 230 Cities, 640,000 Updates
 

Enrico Ronchi auf Twitter: "Even if you do not speak Italian, look at how an Italian newspaper is explaining the #covid-19 rule of 4 m2 per shop client 🙄 What debate on #crowd science can we have in 🇮🇹 with this type of journalism? #BacktoSchool #4×4=4 😜 https://t.co/tbHEmzh1Yy" / Twitter


#Math #Italy @Andrea Borgia @Fernando Santagata

https://twitter.com/Enrico_Evac/status/1260287090824228865
 
Another choir story.

Coronavirus doctor's diary: The strange case of the choir that coughed in January | BBC Health


The writer, Prof John Wright, is a medical doctor and
head of the Bradford Institute for Health Research, and a veteran of cholera, HIV and Ebola epidemics in sub-Saharan Africa.
He's also an epidemiologist, which is:
a medical detective, and like all detectives, the three key clues we are looking for are always: person, place and time.

So when I got an email out of the blue from a Bradford resident saying that she and her friends may have been infected with Covid-19 in January - nearly two months before the first confirmed case of transmission in the UK - I looked for these clues and decided to investigate further.
https://www.bbc.co.uk/news/health-52589449

The prof is @docjohnwright on Twitter:
https://twitter.com/docjohnwright

#health #coronavirus #covid-19 #science #epidemiology
 
Another choir story.

Coronavirus doctor's diary: The strange case of the choir that coughed in January | BBC Health


The writer, Prof John Wright, is a medical doctor and
head of the Bradford Institute for Health Research, and a veteran of cholera, HIV and Ebola epidemics in sub-Saharan Africa.
He's also an epidemiologist, which is:
a medical detective, and like all detectives, the three key clues we are looking for are always: person, place and time.

So when I got an email out of the blue from a Bradford resident saying that she and her friends may have been infected with Covid-19 in January - nearly two months before the first confirmed case of transmission in the UK - I looked for these clues and decided to investigate further.
https://www.bbc.co.uk/news/health-52589449

The prof is @docjohnwright on Twitter:
https://twitter.com/docjohnwright

#health #coronavirus #covid-19 #science #epidemiology
 

A choir decided to go ahead with rehearsal. Now dozens of members have COVID-19 and two are dead | LA Times

the choir outbreak is consistent with a growing body of evidence that the virus can be transmitted through aerosols — particles smaller than 5 micrometers that can float in the air for minutes or longer.

...a study published March 17 in the New England Journal of Medicine found that when the virus was suspended in a mist under laboratory conditions it remained “viable and infectious” for three hours — though researchers have said that time period would probably be no more than a half-hour in real-world conditions.

...it’s possible that the forceful breathing action of singing dispersed viral particles in the church room that were widely inhaled.

...some people happen to be especially good at exhaling fine material, producing 1,000 times more than others.

Amateur singers interested in choral music tend to be older, but the group includes some young adults.

...The youngest of those sickened was 31, but they averaged 67
https://www.latimes.com/world-nation/story/2020-03-29/coronavirus-choir-outbreak

#covid-19 #covid19 #covid 19 #coronavirus #SARS-CoV-2 #SocialDistancing #aerosols #distancing
 

A choir decided to go ahead with rehearsal. Now dozens of members have COVID-19 and two are dead | LA Times

the choir outbreak is consistent with a growing body of evidence that the virus can be transmitted through aerosols — particles smaller than 5 micrometers that can float in the air for minutes or longer.

...a study published March 17 in the New England Journal of Medicine found that when the virus was suspended in a mist under laboratory conditions it remained “viable and infectious” for three hours — though researchers have said that time period would probably be no more than a half-hour in real-world conditions.

...it’s possible that the forceful breathing action of singing dispersed viral particles in the church room that were widely inhaled.

...some people happen to be especially good at exhaling fine material, producing 1,000 times more than others.

Amateur singers interested in choral music tend to be older, but the group includes some young adults.

...The youngest of those sickened was 31, but they averaged 67
https://www.latimes.com/world-nation/story/2020-03-29/coronavirus-choir-outbreak

#covid-19 #covid19 #covid 19 #coronavirus #SARS-CoV-2 #SocialDistancing #aerosols #distancing
 

Die Systemrelevanz lockert sich …


Fußballer werden getestet. Weil systemrelevant? Die Schulen und Kindergärten sollen (wenn auch mit “Abstandsregeln”, dazu gleich noch etwas) wieder aufmachen. Weil “Denkt denn keiner an die Kinder!”) Lehrer, Lehrerinnen, Erzieher, Erzieherinnen werden, im Gegensatz zu Fußballspielern, nicht getestet. Und z.B. im Rhein-Sieg-Kreis überlegt man, ein Abstrichzentrum zu schliessen, weil Abstrichzentren im Rhein-Sieg-Kreis sind nicht ausgelastet. Anscheinend gibt’s neben den Fußballern nicht mehr so viele Systemrelevante.

Mir scheint, die “Systemrelevanz” lockert sich somit langsam auch wieder auf “Normalniveau” zurück … vielleicht sollten alle nochmal zum Abschied leise klatschen?

Apropos Abstandsregeln bei Schülern und Kindern: in Schulbussen sollen nur maximal 15 Schüler einsteigen. Das wird sicherlich gut koordiniert. Zum Beispiel von den Leuten, die auch die Abstände auf den Spielplätzen koordinieren werden. Oder auf Sportplätzen. In Grundschulen findet “Unterricht” an zwei Tagen jeweils für zwei Stunden pro Tag statt, die Kinder werden anschliessend nicht von der OGS betreut. Das entlastet die Eltern wie?

Man könnte noch viel mehr solcher Beispiele aufführen, während die Illusionen von "Nach der Pandemie wird alles besser" wie Seifenblasen aufsteigen und zerplatzen. Währenddessen verstärkt die zweite Pandemie (Dummheit) ihre Wirkung.

P.S. Die Gemeinden, die diverse Lasten und Kontrollen übernehmen sollen, haben inzwischen finanzielle Problem der besonderen Art, wie man am Beispiel der “Haribo-Gemeinde” Grafschaft im Ahrkreis sehen kann: Kommunale Finanzen in der Corona-Krise

#corona #covid-19 #systemrelevant
 
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